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A man suffering from cancer has a colostomy bag from which stool and gas exit. He has a sufficient time for purification every morning when he changes the bag. What is the ruling on his prayer? Is it permissible for him to pray in this condition? Should he pray the missed prayers each day, or should he wait until he is purified to perform the obligatory prayers?
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Peace be upon you and God's mercy and blessings.

Ayatollah Khamenei and Ayatollah Sistani (may Allah protect them):

As long as his body and clothing are not impure, there is no problem with his prayer. The mere presence of the colostomy bag and any impurity within it does not invalidate the prayer.

May you be successful in all good.


Source:

Ayatollah Khamenei (may Allah protect him): Message on Prayer and Fasting, Prayer, Clothing of the Praying Person

Ayatollah Sistani (may Allah protect him): Minhaj al-Salihin, Vol. 1, Impurity of the Body and Clothing of the Praying Person

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