Peace be upon you. According to Grand Ayatollah Sayyid Sistani (may Allah protect him), it is not permissible for her to leave without her husband's permission. He has the right to prevent her from leaving altogether unless it is to fulfill a duty or goes against the norms of good conduct in marriage. Source: [Official Website](
https://www.sistani.org/arabic/qa/3441/).
According to Grand Ayatollah Sayyid Khamenei (may Allah protect him), a wife may not leave her husband's home without his permission, regardless of whether her leaving contradicts his right to enjoyment or not. The husband cannot prevent her from leaving to fulfill a pressing obligation or for a necessity that can only be resolved by her leaving. Source: [Fiqh Al-Wali: Rights of the Wife and Husband in Islam](
https://baqiatollah.net/article.php?id=6099).
May you be successful in all good.